Overview
Positron Emission Tomography (PET) Study
Status:
Completed
Completed
Trial end date:
2009-08-01
2009-08-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The primary purpose is to study the occupancy at the α4β2 neuronal nicotinic receptor's (NNRs) and to determine the relation between plasma concentration of AZD1446 and the occupancy at α4β2 NNRs.Phase:
Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
AstraZeneca
Criteria
Inclusion Criteria:- Physically healthy volunteers
- Body weight between 50 to 100 kg and body mass index (BMI) between 19 and 30 kg/m2
Exclusion Criteria:
- History of any clinically significant disease or disorder
- History of severe allergy/hypersensitivity reactions
- Participation in a PET examination as part of a scientific study during the past
twelve months