Post Operative Hemodynamic Function After Anesthetic Induction With Etomidate for Cardiac Surgery With ECC
Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
Because of its hemodynamic safety, etomidate is widely used for anaesthesia induction of
cardiac surgery. It can also cause adrenal insufficiency during the following 48 hours ( 11
betahydroxylase inhibition ). So it could increase hemodynamic dysfunction caused by the SIRS
following cardiopulmonary bypass.
A previous observational study found more adrenal insufficiency and need for vasopressive
support therapy in the etomidate group versus another propofol induced group.
The aim of our work is to compare hemodynamic dysfunction following induction with etomidate
for cardiac surgery with ECC. The control group would be induced by Propofol. 94 patients
would be included.