Post-operative Treatment of Diabetic Peripheral Arterial Disease Guided by Platelet Reactivity Unit
Status:
Unknown status
Trial end date:
2019-04-01
Target enrollment:
Participant gender:
Summary
To compare the effect of PRU(platelet (P2Y12) reaction units)-guided treatment on the change
in
1. time of initial leg pain and time of termination of exercise test by pain, evaluated on
the graded stationary bicycle test,
2. the lower limb perfusion by using MRI blood oxygenation-level dependent (BOLD) and
dynamic contrast enhancement sequences and measures the extracellular volume fraction
(ECV) as an indicator of fibrosis severity in calf muscles, from one to 52 weeks
post-revascularization in patients with peripheral artery disease who have undergone
endovascular revascularization -/+ bypass surgery for moderate to severe claudication or
ischemic rest pain.