Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis

• Status: Recruiting
• Trial end date: 2020-12-15
• Target enrollment: 0
• Participant gender: All

Summary

Nocturnal enuresis is a worldwide health problem frequently encountered in childhood . It affects 18 % of younger school- age children in Egypt. It is the most frequent (85%) type of enuresis in children (Eberdt-Gołabek et al, 2013), . Nocturnal enuresis includes monosymptomatic nocturnal enuresis with no day time urinary symptoms and non monosymptomatic nocturnal enuresis that accompanied by day time urinary symptoms . It can cause severe psychological and social distress to children and their parents . The currently recommended treatment such as alarms , antidiuretic hormone and anticholenergics are not effective in all children with significant relapse rate . Although it's mechanism of action is not fully elucidated , posterior tibial nerve stimulation is safe and acceptable, with evidence of potential clinical effect for both bladder and bowel dysfunction (Bellette et al, 2009). This study will investigate the effect of posterior tibial nerve stimulation on primary monosymptomatic nocturnal enuresis in children.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Deamino Arginine Vasopressin

Criteria

Inclusion Criteria:

Aged between 5 and 13 years old .

• Experiencing more than two wetting episodes per week .

• Normal urinalysis results .

• Unremarkable urinary tract ultrasaound .

• Normal physical examination.

Exclusion Criteria:

• Diurnal enuresis .

• Faecal soiling .

• Cardiovascular disease .

• Renal disorder .

• Neurological disorders .

• Urinary tract infection