To assess the effects of various postmenopausal estrogen replacement therapies on selected
cardiovascular risk factors, including high density lipoprotein cholesterol, systolic blood
pressure, fibrinogen, and insulin and on osteoporosis risk factors. Conducted in
collaboration with the National Institute of Child Health and Human Development, the National
Institute of Arthritis and Musculoskeletal and Skin Diseases, The National Institute of
Diabetes and Digestive and Kidney Diseases, and the National Institute on Aging. The extended
follow-up is for 3 years focusing on endometrium and breast evaluation.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institute on Aging (NIA)