Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery

• Status: Unknown status
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia. The purpose of this study is to examine the effectiveness of ketamine as a preemptive analgesic as previous studies have shown the involvement of N-methyl-D-Aspartate (NMDA) receptor in neuroplasticity.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tehran University of Medical Sciences
• Treatments: Anesthetics; Ketamine

Criteria

Inclusion Criteria:

• Children aged < = 12 years

• Children scheduled for elective orthopedic surgery with caudal block

• ASA score < = 3

Exclusion Criteria:

• Contraindication for caudal block such as vertebral defect or infection at the site of block

• Disagreement of parents

• Patient's age > 12 years

• ASA score > = 4