Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia

• Status: Not yet recruiting
• Trial end date: 2022-11-10
• Target enrollment: 0
• Participant gender: All

Summary

It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries. Intrathecal morphine added to a spinal anesthesia reduces acute pain after spine surgeries but has side effects, including dose dependent respiratory depression, nausea, vomiting, pruritus, and sedation. Ultrasound guided Erector Spinae Plane Block (ESPB) was first described in 2016.Recent case reports suggest a positive effect of ultrasound guided ESPB on pain for multiple indications including lumbar spine fusion and scoliosis surgery, with a very low risk of complications as there are no structures in close proximity at risk of needle injury.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Fentanyl; Morphine

Criteria

Inclusion Criteria:

• Body mass index (BMI) 25 to 35 kg/m².

• American Society of Anesthesiologist (ASA) physical status I or II.

Exclusion Criteria:

• patient's refusal

• Altered mental status

• Known allergy to study drugs (bupivacaine or morphine)

• Local infection at site of puncture.

• Known case with any pulmonary disease

• Known case with Obstructive sleep apnea (OSA)

• Coagulopathy and /or thrombocytopenia

• Chronic pain

• Severe hepatic or kidney impairment