Postoperative Analgesia of Magnesium Sulfate in Suprascapular Nerve Block Following Shoulder Arthroscopy
Status:
Unknown status
Trial end date:
2019-01-01
Target enrollment:
Participant gender:
Summary
- Arthroscopic shoulder surgeries in adults are accompanied with severe immediate
postoperative pain reported in approximately 45% of patients. For quicker recovery and
rehabilitation of these patients, postoperative analgesia is mandatory.
- Different analgesic modalities have been proposed including parenteral opioids,
intra-articular injection of local anesthetics, interscalene brachial plexus block
(ISB), and a suprascapular nerve block (SSNB), with varying degrees of effectiveness and
multiple reported side effects.
- A recent meta-analysis demonstrates that suprascapular block results in 24-h morphine
consumption and pain scores similar to ISB, so, it may be considered an effective and
safe alternative for interscalene block in shoulder surgery, with less motor
restriction, and fewer complications.
- Different agents are used as adjuvants to local anesthetics during peripheral nerve
block to prolong its analgesic action including magnesium sulfate.
- A meta-analysis by Mengzhu et al., concluded that magnesium sulfate combined with local
anesthetics in perineural nerve blocks provided better analgesic efficacy and may be a
promising analgesic for perineural nerve blocks.
- Antinociceptive effects of magnesium are due to the regulation of calcium influx into
the cell and a non-competitive antagonism of the NMDA receptors