Postoperative Analgesic Effect of Nefopam

• Status: Completed
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Nefopam will be administered to the patients undergoing laparoscopic gastrectomy under the total intravenous anesthesia (TIVA).

The investigators will evaluate whether the nefopam can decrease the total amount of remifentanil administered during the operation, which will reduce the acute opioid tolerance and following consumption of fentanyl during postoperative period.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Bundang Hospital
• Treatments: Nefopam

Criteria

Inclusion Criteria:

• Early or advanced gastric cancer

Exclusion Criteria:

• Refusal

• Use of preoperative analgesic drugs

• Pregnancy

• Recurred gastric cancer

• Seizure

• Cardiac disease

• Monoamine oxidase inhibitor

• Urologic disease

• Previous intrabdominal surgery

• Body mass index > 30 or < 16