Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction
Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
Antibiotics are used routinely in postoperative tissue expander based breast reconstruction
(TE) and autologous flap (AF) breast reconstruction procedures. Closed suction drains are
also used routinely in immediate breast reconstruction to prevent fluid accumulation and
seroma formation at the surgical sites. Antibiotics are most often prescribed as a precaution
since drains can be a source for infection by creating open channels to outside contaminants.
Plastic surgery patients without closed suction drainage devices are usually not placed on
prolonged postoperative antibiotics. Current preoperative surgical antibiotic prophylaxis is
recommended for up to 24 hours only. These recommendations do not take into account the
increased risk of indwelling closed suction drains. A recent survey of plastic surgeons,
conducted by SBUMC investigators, (IRB# 129415) found that Plastic Surgeons are divided as to
extended outpatient administration following TE breast reconstruction.
The study plans to prospectively enroll patients who will undergo immediate breast
reconstruction with TE or AF based breast reconstruction. Using the above data and the
current protocol, the investigators will investigate the optimal antibiotic discontinuation
period for these patients. The investigators hypothesize that the use of 24-hour
perioperative antibiotics in TE or AF based immediate breast reconstruction with closed
suction drainage, does not result in an increased infection rate compared to prolonged
postoperative antibiotic administration.
Phase:
Phase 4
Details
Lead Sponsor:
Stony Brook University
Collaborators:
Plastic Surgery Educational Foundation The Plastic Surgery Foundation