Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Status:
Completed
Trial end date:
2017-02-15
Target enrollment:
Participant gender:
Summary
Tonsillectomy (the surgical removal of the tonsils) is a commonly performed surgery in
children. One risk of tonsillectomy is postoperative bleeding, and this can be more dangerous
in children because their blood volume is lower than adults. Ibuprofen, a nonsteroidal
anti-inflammatory medication (NSAID), is an effective pain medication. Recent guidelines,
published by the American Academy of Otolaryngology, advocated use of ibuprofen after
tonsillectomy. However, NSAIDs are associated with altered platelet function and a
theoretical increased risk of bleeding after surgery. The investigators would like to explore
the effect that ibuprofen has on postoperative bleeding, as well as validate previous studies
demonstrating it is an effective pain medication after tonsillectomy.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts Eye and Ear Infirmary
Collaborators:
Brooke Army Medical Center Madigan Army Medical Center United States Naval Medical Center, Portsmouth United States Naval Medical Center, San Diego