Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

• Status: Completed
• Trial end date: 2019-02-08
• Target enrollment: 0
• Participant gender: Female

Summary

In the present study, midazolam and palonosetron in combination were more effective than palonosetron alone in lowering the incidence and severity of postoperative nausea and vomiting in the initial 2 h after laparoscopic cholecystectomy. Postoperative clinical complications were not different in both groups.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yeungnam University College of Medicine
• Treatments: Midazolam; Palonosetron

Criteria

Inclusion Criteria:

• The patients (aged 20 to 65 years) scheduled for laparoscopic cholecystectomy with American Society of Anesthesiologists (ASA) physical status classification of 1 or 2

Exclusion Criteria:

• The patients with a history of allergy to any other drugs used in this study, gastrointestinal disorder, previous PONV, pregnant woman, breastfeeding woman, use of antiemetics within 24 hours or body mass index > 30 kg/m2