Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
Status:
Terminated
Trial end date:
2021-02-11
Target enrollment:
Participant gender:
Summary
This study will evaluate the use of a local injection around the knee (periarticular) during
total knee replacement (TKR) surgery to see if it reduces postoperative pain levels. The
injection is a combination of various medications which are thought to reduce pain levels.
Approximately 128 patients will participate in this study, half of the patients will receive
this injection during surgery and the other half will receive a saline (salt water)
injection. Pain scores after the surgery will be compared between the two groups.
All patients will also receive a long-acting (24 hours) morphine injection during surgery.
The hypothesis is that those participants receiving intrathecal Duramorph and local
periarticular injections will have improved pain scores and reduced narcotic use when
compared with intrathecal Duramorph alone at 48 hours postoperatively.