Overview
Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA
Status:
Completed
Completed
Trial end date:
2016-12-01
2016-12-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Treatment of postoperative pain with hydromorphone (a strong analgesic) using patient-controlled analgesia with target-controlled infusion compared to conventional patient-controlled analgesia with morphine after elective cardiac surgeryPhase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
University of Erlangen-Nürnberg Medical SchoolCollaborator:
German Federal Ministry of Education and ResearchTreatments:
Hydromorphone
Morphine
Criteria
Inclusion Criteria:- Written informed consent
- Scheduled for elective cardiac surgery involving thoracotomy and subsequent ICU stay
Exclusion Criteria:
- Administration of other analgesics or sedatives, if not administered in stable dosages
for at least 14 days or if not used for premedication and surgery
- Administration of hydromorphone or morphine in the period between screening and
surgery
- Severe hepatic or renal impairment in medical history
- BMI>= 35 ASA>= 4