Postoperative Pain and Angiotensin II Receptor Antagonists
Status:
Unknown status
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
An angiotensin II type 2 receptor (AT2R) antagonist has been assessed for its efficacy in
neuropathic pain with promising results. A considerable number of patients undergoing surgery
under general anesthesia are hypertensive and receive drugs to control high blood pressure,
including angiotensin II receptor antagonists. These drugs may attenuate the acute and/or
chronic postoperative pain or decrease the analgesic requirements after surgery. The aim of
the present study is to assess the early postoperative pain and analgesic requirements in
patients treated with antagonists of the angiotensin II receptors for at least three months
before surgery compared to normotensive patients.
Phase:
Phase 4
Details
Lead Sponsor:
University of Athens
Treatments:
Angiotensin II Angiotensin Receptor Antagonists Angiotensinogen