Postoperative Pain and Headache After Craniotomy

• Status: Withdrawn
• Trial end date: 2022-01-02
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the outcomes of an anesthetic technique which is not synthetic opioid based, on postoperative pain modulation and development of post craniotomy headache against a cohort of patients where an opioid based standard anesthetic technique was used for craniotomy. The hypothesis that is tested is that the use of agents other than synthetic short acting opioids will reduce the amount of postoperative pain and the incidence of headache after surgery.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Steven Edelstein
• Treatments: Anesthetics; Methadone

Criteria

Patient Inclusion Criteria:

• Undergoing Supratentorial, Infratentorial or Skull Base Tumor resection.

• Age 18 to 75

• ASA physical status I to III

Patient Exclusion Criteria:

• ASA physical status IV or V

• Allergies to the medication used for the study

• Pregnant

• Undergoing Emergency, Neurovascular, or Trigeminal Nerve pain procedure

• Liver or renal failure

• Unable to give informed consent