Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine

• Status: Completed
• Trial end date: 2009-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to investigate hypothesis that preoperative administration of epidural clonidine will reduce postoperative pain and systemic inflammatory stress response better than epidural levobupivacaine.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Dubrava
• Treatments: Bupivacaine; Clonidine; Levobupivacaine

Criteria

Inclusion Criteria:

• colorectal resection surgery patients

• preoperative risk of anesthesia and operation, ASA (American Society of Anesthesiologists) physical status I or II

Exclusion Criteria:

• diabetes mellitus

• renal insufficiency

• liver insufficiency

• autoimmune disease

• corticosteroid and immunosuppressive use

• operation time exceeding six hours