Postoperative Sleep Disturbances After Zolpidem Treatment in Fast-track Hip and Knee Replacement

• Status: Unknown status
• Trial end date: 2012-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Sleep after surgery has been found to be very distrubed immediately after major surgery. This is also seen after fast-track hip and knee replacement with length of stay of less than 3 days. Disturbed sleep has many adverse effects i.e. fatigue, possible hyperalgesia and decline in cognitive abilities.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Treatments: Zolpidem

Criteria

Inclusion Criteria:

• Total hip or knee replacement in fast-track setup

• Age 60 years or above

• ASA class 1-3

Exclusion Criteria:

• Anesthesia within the pas 30 days

• Daily use of alcohol > 21 units / week

• Use of anxiolytics or hypnotics within the past 30 days

• Inability to read and understand Danish

• Marked reduction of sight or hearing

• Parkinson's disease or other neurological disaese causing function deficits

• Inability to cooperate to sleep monitoring

• allergy to the drug tested