Postpartum Hypertension, Tight vs Liberal Control Trial

• Status: Completed
• Trial end date: 2021-11-02
• Target enrollment: 0
• Participant gender: Female

Summary

To determine if treatment of less severe hypertension in the postpartum period results in a lower frequency of maternal morbidity.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospitals Cleveland Medical Center
• Collaborator: MetroHealth Medical Center
• Treatments: Antihypertensive Agents

Criteria

Inclusion Criteria:

• Postpartum women aged 18-55 during delivery hospitalization.

• Diagnosis of gestational hypertension, preeclampsia without severe features, or chronic hypertension without requiring antihypertensive therapy who have Blood Pressure at/above 140/90 mmHg on 2 or more occasions more than 4 hours apart and do NOT meet criteria for preeclampsia with severe features and have not received any antihypertensive therapy during their hospitalization

Exclusion Criteria:

• History of chronic hypertension requiring antihypertensive therapy prior to or during pregnancy.

• Diagnosis and/or treatment of preeclampsia with severe features before trial enrollment

• Postpartum patients enrolled in another antihypertensive study (e.g CHAPS)

• Medical comorbidities including: Active connective tissue disease, chronic renal insufficiency, known cardiac disease or cerebrovascular disease.