Postpartum Management of Gestational Hypertensive Disorders Using Furosemide
Status:
Enrolling by invitation
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
- The main purpose of this study is to learn if incorporating a loop diuretic such as
furosemide along with labetalol in the routine management of postpartum gestational
hypertensive disorders could lower the need for additional anti-hypertensive agents to
control blood pressures, improve blood pressures (as measured by systolic blood
pressure, diastolic blood pressure and mean arterial blood pressures), shorten hospital
stays and decrease readmissions for patients with gestational hypertensive disorders.
- Based on a study by Veena et al1, there is reason to believe that the addition of
furosemide to other anti-hypertensives may help decrease the need to add or increase the
dose of medication to control blood pressures. There may be potential to shorten
hospital stays and decrease readmissions, as well. Collecting data will be done using a
prospective, randomized 1:1 controlled study assigning postpartum patients with a
gestational hypertensive diagnosis to either labetalol alone or labetalol plus
furosemide.
- The study will be performed in the postpartum wing of Miami Valley Hospital Main Campus
and would use patients who have consented to participate in the study with enrollees
coming from the OB Staff population.