Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils

• Status: Unknown status
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether fish oil supplementation is effective in the treatment of abnormal fat metabolism in subjects with elevated cholesterolaemia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Western Australia
• Collaborator: National Health and Medical Research Council, Australia

Criteria

Inclusion Criteria:

• Patients with FH (genetically defined LDL-receptor mutation or Dutch score >8) on statin treatment only

• Hypertriglyceridaemia on a random blood sample (triglycerides >1.5mml/L)

Exclusion Criteria:

• Subjects with diabetes mellitus

• major systemic illness or use of steroids or other lipid-regulating drugs (such as niacin, fibrate and colesevelam)

• patients on hypocaloric diets or LDL apheresis; anaemia, haemorrhage and pregnancy.