Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication

• Status: Completed
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This trial assessed the efficacy of potassium competetor acid blocker (P-CAB) in the eradication of H.pylori

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Amoxicillin; Clarithromycin; Esomeprazole; Levofloxacin; Nitazoxanide

Criteria

Inclusion Criteria:

• Age above 18 years of both genders.

• Symptomatic patients who has been diagnosed to be H. pylori positive stool by using H. pylori stool antigen test.

• Patients who did not receive H. pylori eradication regimens before were included in group I of the study (First line eradication regimen).

• Patients who received only one eradication regimen before were included in group II of the study (Second line eradication regimen).

• Patients signing an informed consent.

Exclusion Criteria:

• Patients refusing to sign an informed consent.

• Patients who were on PPIs, P-CABs and/or antibiotics starting one month before inclusion in the study .

• Patients who have chronic debilitating and advanced systemic diseases.

• Patients treated with low dose aspirin and/or non-steroidal anti-inflammatory drugs for a long time.

• Any lactating or pregnant female.