Potentiation of Quetiapine Treatment With Lithium or Aripiprazole in Bipolar 1 Nonresponders Patients

• Status: Unknown status
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether Bipolar I Disorder refractory treatment with Quetiapine monotherapy could be better potentiated with Lithium or Aripiprazole. The investigators hypothesized that Lithium or Aripiprazole would provide similar compliance and tolerability in maintenance treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo
• Treatments: Aripiprazole; Central Nervous System Depressants; Lithium Carbonate; Molecular Mechanisms of Pharmacological Action; Quetiapine Fumarate

Criteria

Inclusion Criteria:

• Clinical diagnosis of Bipolar Disorder, type I, in current episode (manic/hypomanic, mixed or depression)

• The patient or his (her) legal representative should understand the nature of the study and sign the Informed Consent

Exclusion Criteria:

• Schizophrenia or schizoaffective disorder

• Mental retardation

• Unstable clinical diseases