Overview

Povidone Iodine Nasal Application to Prevent Intraoperative Spread of SARS-CoV-2

Status:
Not yet recruiting
Trial end date:
2025-04-01
Target enrollment:
0
Participant gender:
All
Summary
The primary aim is to test whether preoperative asepsis with 5% nasal povidone iodine versus no preoperative asepsis with 5% nasal povidone iodine reduces proximal and distal SARS-CoV-2 transmission in operating rooms among patients who are acutely infected with SARS-CoV-2. The secondary aim is to test viral infectivity.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Randy Loftus
Collaborator:
3M
Treatments:
Povidone
Povidone-Iodine
Criteria
Inclusion Criteria:

- Adult patients

- Undergoing surgery (elective, urgent, or emergent)

- Requiring general anesthesia

- Acutely infected (<= 10 days from diagnosis) with SARS-CoV-2

Exclusion Criteria:

- Not general anesthesia

- Not acutely infected (<= 10 days from diagnosis) with SARS-CoV-2

- Allergy to povidone iodine

- Unable to provide consent

- Pregnant individuals