Pralatrexate and Fluorouracil in Treating Patients With Recurrent Solid Tumors
Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Pralatrexate may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Drugs used in chemotherapy, such as fluorouracil, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Giving pralatrexate together with fluorouracil may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of pralatrexate when
given together with fluorouracil in treating patients with recurrent solid tumors