Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the effects of combining metformin and atorvastatin
treatment in patients with newly diagnosed breast cancer during the interval between breast
biopsy and surgery.
This study is designed to assess whether tumor proliferation, as measured by the natural log
expression of Ki-67 staining of breast tumor cells, is reduced following approximately 2
weeks of treatment with the combination of metformin plus atorvastatin in patients with newly
diagnosed breast cancer.