Pre-emptive Pregabalin on Attenuating Maternal Anxiety And Stress Response To Intubation During Caesarean Section
Status:
Recruiting
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
There is exaggerated neuroendocrine stress response to laryngoscopy and endotracheal
intubation during the Induction to anesthesia-delivery (I-D) period under light anesthesia.
Mechanical stimulation of laryngeal proprioceptors elicits increased secretion of cortisol
and catecholamine with subsequent elevation of blood pressure from 40 to 50 % and heart rate
up to 20 % during direct laryngoscopy and endotracheal intubation