Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain

• Status: Recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Postcraniotomy pain remains a common phenomenon in the neurosurgery field. Managements for postcraniotomy pain are to be standardised and optimized. In the proposed study, the investigators aim to provide a novel regional non-invasive prophylactic strategy for postcraniotomy pain by utilizing Lidocaine 5% plaster.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Tiantan Hospital
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Age of 18 or older

• American Society of Anesthesiologists status I or II

• Registered for elective craniotomy

• Informed consent for participation in the trial

Exclusion Criteria:

• Allergy to lidocaine or the hydrogel plaster

• Chronic headache, craniofacial pain or neuralgia

• Glasgow Coma Scale less than 15

• Current or previous cardiovascular or cerebrovascular accident

• Expected delayed recovery or extubation

• Uncontrolled arrhythmia

• History of intracranial operation

• Emergency or revision craniotomy

• Mental illness, psychiatric drug use or alcohol abuse

• Failure to understand the use of a 100 mm VAS or the PCA