Pre-hospital Morphine Titration : Comparison of 0,05 Versus 0,1 mg/kg

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Efficacy and safety of morphine titration on acute pain in emergency medical mobile units with initial bolus of 0.1 mg/kg plus 0.05 mg/kg versus morphine titration with initial bolus of 0.05 mg/kg plus 0.025 mg/kg

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Toulouse
• Treatments: Morphine

Criteria

Inclusion Criteria:

• Severe, acute pain defined by a VRS of 60/100 or higher

• Male or female over 18 years

• Cared by a medical emergency care unit

• Written informed consent

• Affiliated to social security

Exclusion Criteria:

• A known opioid or paracetamol hypersensitivity

• Patient not agree ta participate at the study

• Pregnancy

• Uncontrolled epilepsia

• Incapacity to understand the VRS

• Renal, respiratory, or liver disease

• Patients who have received sedative drugs or alcohol (< 6h)

• Acute respiratory, haemodynamic or neurologic failure

• Patients who have already received an analgesic (< 6h)

• Drug addiction

• Patients under protection of justice