Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)
Status:
Active, not recruiting
Trial end date:
2028-04-01
Target enrollment:
Participant gender:
Summary
This is a window-of-opportunity umbrella platform trial enrolling non-metastatic resectable
colorectal patients selected for the presence of a specific targetable molecular alteration.
The study aims to test the activity of specific targeted agents/combinations given as a
short-course pre-operative strategy, matched with the specific alteration detected, followed
by standard of care surgery.