Pre-operative Treatment With Erythropoietin and Iron Supplement in Cardiac Surgery

• Status: Terminated
• Trial end date: 2017-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Pre-treatment of patients with erythropoietin subcutaneously and iron supplement intravenously, in order to create a clinical pathway to minimize transfusion of red blood cells in a selected group of cardiac patients with an increased risk for blood transfusions in our cardiac surgery program.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Catharina Ziekenhuis Eindhoven
• Treatments: Epoetin Alfa; Iron

Criteria

Inclusion Criteria:

1. Undergoing isolated Coronary Artery Bypass Grafting operation or Aortic Valve Repair (AVR).

2. Preoperative Hb < 7 mmol/l.

Exclusion Criteria:

1. Off pump surgery.

2. Combination surgery.

3. Re-operation.

4. Emergency operation.

5. Patients with bleeding disturbances; e.g, hemophilia and patients with chronic liver disease.

6. Concomitant use of cyclosporine prior to, during or following surgery.

7. Female patients who are pregnant or planning to become pregnant.