Prednisone in Chronic Rhinosinusitis Without Nasal Polyps

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether prednisone is effective in the treatment of chronic rhinosinusitis without nasal polyps in adult patients.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Chile
• Collaborator: Sociedad Chilena de Otorrinolaringología, Medicina y Cirugía de Cabeza y Cuello
• Treatments: Prednisone

Criteria

Inclusion Criteria:

• Diagnosis of CRSsNP as recommended European Position Paper on Rhinosinusitis and Nasal Polyps 2012

Exclusion Criteria:

• Treatment with oral corticosteroids or topical corticosteroids the last 4 weeks.

• Previous surgical treatment for CRSsNP

• History of diabetes mellitus and / or glaucoma and / or decompensated hypertension and / or gastric ulcer.

• Pregnancy.

• History of cystic fibrosis, primary ciliary dyskinesia, immunodeficiency, allergic fungal sinusitis, nasal polyps, nasal tumors, hepatic or renal dysfunction.

• Hypersensitivity to prednisone