Preemptive Analgesia With Celecoxib for Acute Dental Pain Management

• Status: Recruiting
• Trial end date: 2024-04-22
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered preemptively to patients prior to impacted third molar surgery. .

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston
• Treatments: Acetaminophen; Celecoxib

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) physical status classification 1 or 2

• at least 1 impacted mandibular third molar planned for extraction

Exclusion Criteria:

• ASA 3 or higher for physical status classification

• severe pericoronitis associated with third molar to be extracted

• any known allergies to NSAIDs, aspirin, acetaminophen, sulfa drugs

• history of cardiovascular or cerebrovascular disease

• hepatic disease or impairment

• pregnancy