Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
Status:
Not yet recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
The goal of this randomized clinical trial is to compare patient-reported pain and oral
health-related quality of life during the first postoperative week following extraction and
bone graft surgery in patients who received preemptive ibuprofen versus placebo. Participants
will receive ibuprofen 600mg or placebo by mouth with water 1 hour prior to extraction and
bone graft surgery.
The primary question it aims to answer is:
• Does preemptive ibuprofen have an effect on postoperative pain 1 hour following extraction
and bone graft surgery compared to placebo?
Secondary questions are:
- Does preemptive ibuprofen have an effect on pain during the first 3 postoperative hours
and 7 postoperative days following extraction and bone graft surgery compared to
placebo?
- Does preemptive ibuprofen have an effect on oral health-related quality of life during
the 7 postoperative days following extraction and bone graft surgery compared to
placebo?