Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide

• Status: Not yet recruiting
• Trial end date: 2024-04-30
• Target enrollment: 0
• Participant gender: All

Summary

Even with a large number of agents with action desensitizing agents (which reduce the symptoms of tooth sensitivity) available in market, there is no treatment considered the gold standard, which is completely effective for treat sensitivity caused by tooth whitening treatment. In this sense, the Pregabalin (PG), a medication with analgesic and anti-inflammatory action, can be a effective alternative to control this discomfort.

Therefore, the objective of this project is to evaluate the effect of applying a gel containing the 10% Pregabalin associated with in-office teeth whitening, in reducing sensitivity dental.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universidade Federal do Para
• Treatments: Fluorides; Listerine; Pregabalin; Sodium Fluoride

Criteria

Inclusion Criteria:

• Participants must have at least 28 teeth in the cavity

• good oral and general health

Exclusion Criteria:

• active caries or periodontal disease

• visible cracks in front teeth upper or lower

• with evident malocclusion

• restorations and prosthetics in teeth anterior teeth

• gastroesophageal disorders

• severe internal tooth discoloration (tetracycline , fluorosis or pulped teeth)

• dentin exposure in anterior teeth and /or later

• parafunctional habits

• tooth sensitivity

• whitening treatment prior to or undergoing orthodontic treatment

• Furthermore, smokers, pregnant or breastfeeding women do not will be included.