Pregabalin for Abdominal Pain From Adhesions

• Status: Terminated
• Trial end date: 2008-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate if pregabalin demonstrates significant reduction in abdominal pain from adhesions.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Henry Ford Health System
• Collaborator: Pfizer
• Treatments: Gabapentin; Pregabalin

Criteria

Inclusion Criteria:

• Must have history of prior surgery and documented adhesions during laparoscopy or open laparotomy within 5 years

• Must have undergone an evaluation to exclude other causes of abdominal pain

• Abdominal pain must be present for greater than three months duration

Exclusion Criteria:

• Patients that are pregnant or breast feeding

• Prior treatment with gabapentin, pregabalin or demonstrated sensitivity to these drugs

• Patients who are immunocompromised

• Patients with significant hepatic or renal insufficiency, or any significant hematologic disorder

• History of illicit alcohol or drug abuse within one year

• Documented serious or unstable medical or psychological condition

• Malignancy within the past 5 years other than in situ squamous cell carcinoma of the skin