Premedication Trial for Tracheal Intubation of the NEOnate
Status:
Completed
Trial end date:
2020-04-15
Target enrollment:
Participant gender:
Summary
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs
"atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the
neonate.
Primary outcome: pulse oxymetry value < 80% for more than 60 seconds. Secondary outcomes:
number of attempts, duration of the procedure, changes in physiologic parameters, short- and
long-term neurodevelopmental outcome.
Hypothesis: "atropine + propofol" compared to "atropine+atracurium+sufentanil" will
significantly reduce the frequency of severe hypoxemia.