Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

• Status: Withdrawn
• Trial end date: 2020-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This randomized control trial will compare opioid use, pain, and functional outcomes following decompression surgery for single-level lumbar radiculopathy in patients who undergo placement of corticosteroid epidural injection within 2 weeks prior to surgery compared to those who do not. The hypothesis of this study is that patients who receive the preoperative corticosteroid injection will have less reduced postoperative opioid use, as well as earlier mobilization, reduced length of stay, and faster return to work compared to control patients who do not receive the injection.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lahey Clinic

Criteria

Inclusion Criteria:

1. Patients 30-75 years of age

2. Patients diagnosed with diagnoses with single level unilateral lumbar radiculopathy

3. Patients diagnosed with spinal stenosis or disc herniation

4. Patients who have a history of > 6 weeks of at least 1 conservative treatment

5. ASA < III

Exclusion Criteria:

1. Patients who have undergone previous lumbar spinal surgery at index level

2. Patients diagnosed with spondylolisthesis at index level

3. Patients currently taking anti-coagulant therapy

4. Active treatment of major psychiatric condition such as major depression and/or anxiety disorder.

5. Patients currently seeking or receiving workers compensation

6. Patients who have undergone previous corticosteroid injection at index level

7. Morbid obesity defined as BMI > 40

8. Patients with history of chronic opioid use

9. Patients with a contrast dye allergy

10. Extruded disc fragment