Preoperative Decolonization and Surgical Site Infections in Orthopaedic Surgery - 2 Year Outcome in Prosthetic Surgery

• Status: Completed
• Trial end date: 2020-06-30
• Target enrollment: 0
• Participant gender: All

Summary

Surgical site infections in orthopaedic surgery are a major problem. Decolonization has been suggested to reduce infection rates. The study was designed as a prospective, controlled, randomized, single-blinded trial to assess the influence of a decolonization procedure in S. aureus and non - S. aureus carriers. In this trial the 2 - year outcome in the subpopulation of prosthetic elective orthopaedic surgery will be evaluated.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lindenhof AG; Lindenhofgruppe AG
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Mupirocin

Criteria

Inclusion Criteria:

• older than 16 years

• planned elective orthopedic procedure

• Decolonization protocol can be performed timely

Exclusion Criteria:

• No orthopedic prosthetic surgery planned

• Allergy to mupirocin or chlorhexidine

• Presence of a nasal foreign body

• No informed consent

• undergoing treatment/surgery for a documented infection

• already participating in the study