Preoperative Gabapentin Versus Bisoprolol for Hemodynamic Optimization During Sinus Surgery
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
the current study hypothesized that Gabapentin can be effective as Bisoprolol in reduction of
intraoperative bleeding, improving the operative's field visibility and increase the surgeon
satisfaction via optimization of blood pressure and heart rate .
A prospective randomized double blinded controlled study. Eligible patients were randomized
according to random list generated software and allocated into 3 equal and matched groups (15
patients in each group):-
- Group G: gabapentin group in which Patients were premedicated with oral gabapentin 1200
mg (Conventin 400mg; Evapharm) with sips of water, 2 hours before induction of
anesthesia.
- Group B: bisoprolol group in which Patients were premedicated with oral bisoprolol 2.5
mg ( Concor 2.5mg ; Merck/Amoun ) with sips of water, 2 hours before induction of
anesthesia.
- Group C: control group in which Patients were premedicated with oral placebo with sips
of water, 2 hours before induction of anesthesia.