Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE).

• Status: Unknown status
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To assess the effects of prolonged preoperative gabapentin treatment (10 days) on chronic pain after thoracotomy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Lille
• Collaborator: University of Lille Nord de France
• Treatments: Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• age > 18 years

• elective lung resection via thoracotomy

Exclusion Criteria:

• extended pleurectomy and chest wall resection

• previous ipsilateral thoracotomy

• previous ipsilateral radiotherapy

• thoracotomy for pyothorax

• chest injury

• palliative surgery

• contraindicated placement of a thoracic epidural catheter

• allergy to medications on protocol

• pre-existing pain syndrome

• current treatment with morphine, gabapentin, pregabalin, anticonvulsivants or tricyclic antidepressants

• a history of past or current drug addiction

• severe hepatic, renal or cardiovascular disorders

• inability to understand the study protocol or to answer the questionnaires on pain and quality of life

• severe psychiatric disorders

• incompetent adults under some form of guardianship

• refusal of the protocol

• persons without social security coverage

• pregnant or lactating woman