Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
Status:
Not yet recruiting
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
This study will recruit women scheduled to undergo vaginal apical suspension surgery (either
uterosacral ligament suspension or sacrospinous ligament fixation) with or without other
prolapse or anti-incontinence procedures. Participants will be randomized 1:1 to preoperative
gabapentin or preoperative placebo (both patients and investigators will be blinded). Note
the control group will receive preoperative acetaminophen/celecoxib/placebo and the treatment
group will receive preoperative acetaminophen/celecoxib/gabapentin (preoperative
acetaminophen/celecoxib are part of our current ERAS protocol). The primary outcome will be
postoperative opioid use in the first 24 hours postoperatively measured in morphine milligram
equivalents.