Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
Despite improvements in analgesic treatment following total knee arthroplasty (TKA) for
osteoarthrosis, a substantial part of patients still have severe acute pain after surgery. It
has been suggested that preoperative degree of intraarticular inflammation is associated to
postoperative degree of pain and level of function. Furthermore it is known, that patients
with preoperative inflammation have hyperalgesia and severe movement related pain.
The aim of this study is to investigate the effect of a preoperative intraarticular injection
of Methylprednisoloneacetate in reducing acute postoperative pain after total knee
arthroplasty in patients with signs of severe pre-operative inflammation and pain.