Overview

Preoperative Oral Antibiotics With vs Without Mechanical Bowel Preparation to Reduce Surgical Site Infections Following Colonic Resection: an International Randomized Controlled Trial.

Status:
Not yet recruiting

Trial end date:
2023-05-01

Target enrollment:

Participant gender:

Summary

The ORALEV Study found that preoperative oral antibiotics can reduce the incidence of surgical site infections after colonic resection, compared with no preparation. The role of mechanical bowel preparation in patients needing colonic surgery is yet to be elucidated. No randomised controlled trials have assessed the impact of mechanical bowel preparation combined with oral antibiotics on the incidence of surgical site infections after colonic surgery, compared with oral antibiotics only.

Phase:

Phase 4

Details

Lead Sponsor:

Hospital Universitari Vall d'Hebron Research Institute

Treatments:

Anti-Bacterial Agents
Antibiotics, Antitubercular
Cefuroxime
Cefuroxime axetil
Citric Acid
Magnesium Oxide
Metronidazole
Picosulfate sodium
Sodium Citrate