Preoperative Oral Pregabalin Effect on Inhalational Anesthetic Requirements ln Hysterectomy Under General Anesthesia

• Status: Completed
• Trial end date: 2017-09-20
• Target enrollment: 0
• Participant gender: Female

Summary

In this study the investigators hypothesized that preoperative pregabalin tablet (150 mg orally ) may be effective in reducing intraoperative isoflurane requirements needed to maintain intraoperative hemodynamics within ± 20% of baseline measurement and/or attenuates hemodynamic response to endotracheal intubation in female patients ASA I or II , aged 18-60 years, schedule for elective abdominal hysterectomy surgery under general anesthesia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nesrine El-Refai
• Treatments: Anesthetics; Anesthetics, Inhalation; Pregabalin

Criteria

Inclusion Criteria:

• Female patients, aged 18-60 year scheduled for elective abdominal hysterectomy surgery under general anaesthesia.

• American Society of Anaesthesiology (ASA) physical status I or II.

Exclusion Criteria:

• American Society of Anaesthesiology (ASA) physical status ≥ III.

• Allergy or hypersensitivity to pregabalin.

• Patient on calcium channel blocker or anticonvulsant.