Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery
Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
This is a feasibility study which will evaluate the effects of pre-operative treatment of
DCIS of the breast with palbociclib. Patients with biopsy-proven DCIS are eligible for the
study.
There will be 2 independent and unrelated study groups of 12 patients each, for a total of 24
patients:
1. Group A, of male or female patients treated with palbociclib single agent (n=12);
2. Group B, untreated, of male or female patients who consented translational studies in
blood, as well as diagnostic and definitive surgical specimen, but not the pre-operative
treatment with palbociclib (n=12).