Preoperative Panitumumab and Radiotherapy in Rectal Cancer
Status:
Terminated
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the activity of panitumumab in combination with
standard preoperative radiotherapy in locally advanced rectal cancer, followed by complete
surgery and adjuvant chemotherapy.
The main hypothesis of the study is that the association of EGFR-targeting agent and
radiation therapy could be as effective or even improve the rate of pathological complete
tumoral response with fewer toxicities in comparison to the standard of care using
chemoradiation therapy.
Phase:
Phase 2
Details
Lead Sponsor:
Cliniques universitaires Saint-Luc- Université Catholique de Louvain