Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting
Status:
Unknown status
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess the safety and efficacy of S-1 and oxaliplatin
combined with radiation by Phase I/II study.
The purpose of this study is as follows,
- In phase I, to determine the dose limiting toxicities (DLTs) and the maximum tolerated
dose (MTD).
- In phase II, to evaluate the antitumor effect (pCR rate) and the safety .