Preoperative Vaginal Dinoprostone Versus Misoprostone in Abdominal Myomectomy

• Status: Completed
• Trial end date: 2023-02-20
• Target enrollment: 0
• Participant gender: Female

Summary

Aim and objectives; To compare the efficacy of preoperative administration of dinoprostone 20 mg versus 400 ug misoprostol vaginally in decreasing the amount of bleeding during abdominal myomectomy

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Beni-Suef University
• Treatments: Dinoprostone; Misoprostol

Criteria

Inclusion Criteria:

• Age 30-50 years

• all cases with uterine fibroid not responding to medical treatment and indicated for myomectomy.

Exclusion Criteria:

• contraindications to dinoprostone or misoprostol,

• active PID,

• history of pelvic/ ovarian endometriosis,

• females who had pre-operative mifepristone, GnRH analog or orally contraception drugs, earlier myomectomy.