This is a single-centre, randomised-controlled trial, comparing management of preschool
wheeze. It specifically aims to compare management of preschool wheeze using current clinical
guidelines to management determined by eosinophilic inflammation and infection. Participants
will be children aged 1-5 years who have recurrent wheezing and will be allocated to one of
two treatment groups, either current clinical care or pathological phenotype based
management. They will be asked to make 2 study visits to the Royal Brompton Hospital over the
course of 4 months.
Phase:
Phase 2
Details
Lead Sponsor:
Imperial College London
Collaborator:
National Institute for Health Research, United Kingdom